Metabolomics
Aptiance provides LC-MS based metabolomic techniques for trouble shooting problems in drug discovery and metabolism. We provide specific and quantitative analyses of the bioactive components and their metabolites in biometrics. State of the art high resolution accurate mass data obtained from LCMS-QTOF enables us to carry out differential analyses between control and test groups to figure out differences in their profiles. This can have serious implications for drug discovery and development.
Currently we provide the following metabolomic services:
Aptiance provides LC-MS based metabolomic techniques for trouble shooting problems in drug discovery and metabolism. We provide specific and quantitative analyses of the bioactive components and their metabolites in biometrics. State of the art high resolution accurate mass data obtained from LCMS-QTOF enables us to carry out differential analyses between control and test groups to figure out differences in their profiles. This can have serious implications for drug discovery and development.
Currently we provide the following metabolomic services:
- Sample preparations (Chemical or biological)
- LC-MS Method development,
- Method Validation (FDA guidelines, currently SOP only)
- Separation, identification and isolation of metabolites
- Quantitative determination of one or more metabolites
- Synthetic preparation of External/Internal standards and Metabolites
- Synthesis of Metabolites
- Metabolite Profiling (differential Expression analysis) to find statistically significant metabolite.
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